The Foundation has not staff employed but is benefiting of the facilities and staff of the University of Palermo attributed to the host structure. Its activity are decided by a Board of Directors on the basis of the advises provided by the Scientific Committee.

The Board of Directors (2021-2026)
- Prof. Francesco M. Raimondo (Palermo), pro tempore coordinator of the project "Herbarium Mediterraneum" designated by the Organization for the Phyto-Taxonomic investigation of the Mediterranean Area, PRESIDENT
- Prof. Dr. Werner Greuter (Berlin), co-opted in accordance with art. 8, the last paragraph of the Statute, VICE PRESIDENT
- Prof. Massimo Midiri (Palermo), Rector of the University of Palermo, COMPONENT
- Prof. Benito Valdés (Seville), Chairman of the Scientific Committee of the Foundation, COMPONENT
- Dott. Mario Candore (Palermo), Director General Regional Department of Rural Development and territorial of the Sicilian Region, COMPONENT
- Arch. Selima Giorgia Giuliano (Palermo), Superintendent of Cultural and Environmental Heritage of Palermo, COMPONENT
- Prof. Attilio Carapezza (Palermo) representing the Nature Museum Francesco Minà Palumbo Castelbuono, COMPONENT
- Prof. Gianniantonio Domina (Palermo) General Secretary of the Organization for the Phyto-Taxonomic investigation of the Mediterranean Area, COMPONENT
- Arch. Lina Bellanca (Palermo), representing the city of Palermo, COMPONENT
- Prof. Giuseppe Venturella (Palermo), co-opted in accordance with art. 8, the last paragraph of the Statute, COMPONENT
- Prof. Pietro Mazzola (Palermo), co-opted in accordance with art. 8, the last paragraph of the Statute, COMPONENT

The Scientific Committee (2021-2026)
- Prof. Benito Valdés (Seville), representing the Optima (PRESIDENT)
- Prof. Francesco M. Raimondo (Palermo), representing the Optima (COMPONENT)
- Prof. Werner Greuter (Berlin), representing the Optima (COMPONENT)
- Prof.Georgia Kamari (Patras), representing the Optima (COMPONENT)
- Prof. Gianniantonio Domina (Palermo), representing the University of Palermo (COMPONENT)
- Dr. Stephen L. Jury (Reading), representing the Optima (SUBSTITUTE)

The Board of Auditors (2021-2026)
- Rag. Rosaria Mazzola
- Prof. Vivienne Spadaro
- Dott. Patrizia Campisi